euthanasia sodium pentobarbital - An Overview

pentobarbital will reduce the extent or impact of nisoldipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

pentobarbital will lower the extent or impact of lonafarnib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib can be a sensitive CYP3A4 substrate. Coadministration with potent or average CYP3A4 inducers is contraindicated.

pentobarbital will lower the level or result of theophylline by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will decrease the level or outcome of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

CYP3A4 inducers may raise the formation from the neurotoxic/nephrotoxic ifosfamide metabolite, chloroacetaldehyde. Intently keep track of clients getting ifosfamide with CYP3A4 inducers for toxicities and contemplate dose adjustment.

pentobarbital will decrease the level or effect of bosentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.

pentobarbital will decrease the extent or impact of oxybutynin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.

pentobarbital will minimize the extent or outcome of ramelteon by influencing hepatic enzyme CYP2C9/10 more info metabolism. Minimal/Importance Unfamiliar.

pentobarbital will reduce the level or outcome of zonisamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.

Reserve concomitant prescribing of those drugs in sufferers for whom other cure options are insufficient. Restrict dosages and durations on the least expected. Observe carefully for signs of respiratory despair and sedation.

pentobarbital will lower the extent or outcome of cortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will decrease the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

pentobarbital will reduce the extent or impact of nimodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unknown.

With therapeutic doses of TCAs, barbiturates maximize metabolism and reduce blood concentrations of TCAs.